Conference Notes from 5/10

Lightning Lectures with Drs. Huttner and Loche

Foreign body aspiration
-	Presentation
o	Usually sudden onset coughing and choking
o	Can develop stridor, cyanosis, respiratory arrest
-	Diagnosis
o	CXR negative in > 50% of tracheal foreign bodies, 25% of bronchial foreign bodies
o	Bronchoscopy = gold standard
-	Treatment
o	If conscious, back blows, abdominal thrusts, chest thrusts
o	Laryngoscopy to remove with Magill forceps
o	Intubation can be used to push object into R mainstem bronchus and allow aeration of one lung

Mastoiditis
-	Usually results from untreated otitis media – mastoid air cells are continuous with middle ear
-	Most common cause is strep pneumoniae or strep pyogenes
-	Diagnosis
o	Clinical in most cases
o	Consider CT in toxic appearing children or if extracranial complications
-	Treatment
o	If not recurrent and no abx in 6 months > Unasyn q6h at 50 mg/kg
o	If recurrent or recent abx > Zosyn q6h 75 mg/kg
o	Add Vanc if septic
o	Treat 7-10 days IV, follow by 4 weeks of po antibiotics
o	Consult ENT
-	Complications – meningitis, CNS abscess, venous sinus thrombosis

Malignant Otitis Externa
-	Usually adults with diabetes
-	Caused by Pseudomonas in 95% of cases
-	Presentation – often have granulation tissue in the inferior EAC and purulent drainage
-	Initial treatment is with ciprofloxacin IV 400 mg q8h
-	Consider Zosyn for severe infection or immunocompromise 
-	Can lead to osteomyelitis of the skull base or TMJ

ENT Lecture with Dr. Vinh

Airway complications: Tracheostomy vs Laryngectomy
-	Tracheostomy: ask three questions
o	Why does patient have tracheostomy?
	Most common is failure to wean from vent > still able to intubate from above
	Anatomic obstruction from tumor, etc. > typically will be difficult to intubate from above
o	How long has trach been present?
	Takes at least 1 week for tract to mature
o	What type of trach is it? Cuffed or uncuffed?

-	Laryngectomy
o	Trachea is directly connected to skin
o	There is no airway from the nose and mouth
  cannot bag over mouth or intubate from above
o	Can use pediatric size BVM over stoma to bag

Complicated airways
-	Ludwig’s Angina – submandibular space infection which causes upper airway obstruction
o	Odontogenic infections account for ~70% of cases
o	Treatment with Unsyn and Vanc + surgical drainage and/or tooth extractions
-	Angioedema
o	Treatment
	Corticosteroids, antihistamines, epinephrine, stop ACE-Is
o	Always perform flexible laryngoscopy – laryngeal edema may be much worse than visible oropharyngeal edema
-	Peritonsillar abscess
o	Management – antibiotics (unasyn or augmentin), +/- steroids, +/- I&D or needle aspiration
o	Can have trismus (usually due to pain)
-	Epiglottitis 
o	Majority of cases caused by staph and strep – empiric antibiotics with Vanc and Unasyn
o	Swelling of the larynx causes disproportionate narrowing of the airway compared to other anatomic sites
-	Head and neck cancer

Securing the airway
-	Supportive measures
o	Treat underlying cause
o	Supplemental O2
o	Racemic epi – useful for laryngeal edema
o	Heliox 
-	Sedation/anesthesia?
o	Anesthesia causes airway obstruction due to loss of muscle tone, suppression of protective arousal responses and decrease in respiratory reserve
-	Make plan for intubation
o	Fiberoptics for oropharyngeal obstruction
o	Cricothyroidotomy for laryngeal obstruction
-	Fiberoptic intubation
o	Transoral vs transnasal
o	Local anesthesia is key if unable to sedate  atomizers and 4% lidocaine
o	Afrin and serial dilation with nasal trumpets

Transfer Center Lecture with Dr. Mallory

-	Similar to air traffic control – connects to physicians working clinically and directs patients to appropriate facilities
-	RNs and medical directors working in the transfer center have knowledge of which services are offered at which hospitals and are able to direct calls accordingly
-	Also have up to date information about specific bed availability at different facilities

Ophthalmology for the ED with Dr. Rashidi

-	Pupillary exam
o	Afferent pupillary defect – tested with swinging flashlight test
o	Test direct response and consensual response
o	Shape of pupil is important to check
-	Visual acuity
o	If unable to read letters/numbers, at least relay if patient can count fingers, detect light, etc.
-	Intraocular pressure
o	Up to 21 mmHg is normal

-	Corneal abrasions treatment
o	Smaller abrasions – erythromycin ointment 3-4x/day x4-5 days
o	Wood, ticks, fingernail – moxifloxacin drops 4x/day x4-5 days
o	Large, central, or concerning features – consult ophtho

-	Chemical burns
o	Use Morgan lens
o	Check pH before using any drops – normal 6.5 – 7.5 

-	Traumatic iritis/mydriasis
o	Treat with dilating drops (atropine or cyclopentolate 0.5 or 1%)

-	Hyphema 
o	Needs ophtho consult to check for posterior trauma

-	Retrobulbar hemorrhage
o	Causes orbital compartment syndrome – can result in irreversible vision loss
o	Needs lateral canthotomy and cantholysis

-	Eyelid laceration
o	Medial lacerations – concern for canaliculus injury

-	Acute angle closure glaucoma
o	IOP lowering drops – timolol, apraclonidine, latanoprost, pilocarpine
o	IV Diamox 500 mg
o	IV mannitol 1-2g/kg over 45 minutes

Conference Notes from 5/3/23

Ejection Fraction and Cardiac Imaging with Dr. Baker

  • Normal EF findings on POCUS – wall thickening and symmetric contraction during systole, anterior leaflet of mitral valve slapping interventricular septum
  • Ways to calculate EF using POCUS
  • EPSS = End point septal separation
    • Less than 7 mm = normal
    • Greater than 10 mm = reduced EF
  • Fractional shortening – measures LV in systole and diastole
  • Fractional area change – uses RV volumes in end systole and end diastole to calculate EF
  • Simpson Biplane method – US will calculate change in volume of the LV between end diastole and end systole

Lightning Lectures with Drs. Gellert and Wells

  • Ludwig’s Angina
    • Rapidly progressive gangrenous cellulitis of the submandibular spaces
    • Polymicrobial
    • Clinical diagnosis, imaging not required
    • Management
      • Airway – preferred awake fiberoptic intubation
      • Antibiotics – Unasyn OR Rocephin + Vanc OR Clindamycin
      • Surgical – Tooth extraction, debridement
  • Retropharyngeal Abscess
    • Abscess between posterior pharyngeal wall and prevertebral fascia
    • Late findings – stridor, respiratory distress, drooling, neck stiffness
    • Complications
      • Acute Necrotizing Mediastinitis (~25% mortality)
      • Sepsis
      • Aspiration
      • Lemierre’s syndrome – septic thrombophlebitis of IJ
    • Diagnose with CT neck w/contrast
    • Management
      • ENT consultation
      • Antibiotics – Cllindamycin 600-900 mg IV or Cefoxitin 2 mg IV or Augmentin 3 g IV
  • Peritonsillar Abscess
    • Abscess between tonsillar capsule, superior constrictor muscles
    • Classic “hot potato voice”, uvula deviation
    • CT can help differentiate between cellulitis, RPA
    • Management
      • I&D or Needle Aspiration
        • For I&D use scalpel to incise 1 cm deep into abscess cavity
        • Use guard on scalpel to prevent deeper incision and vascular injury
      • Medications – Decadron 10 mg IV + Rocephin 2 g IV + Clindamycin 600 mg IV
      • Need ENT/PCP f/u in 24-48 hours if not admitted

Tracheostomy Complications with Drs. Lehnig and Nelson

  • Approximately 1% of tracheostomies associated with major complications
    • 50% mortality with major complications
    • Usually occur after 1 week
  • Emergent complications = decannulation, obstruction, hemorrhage
    • Decannulation
      • Replace ASAP as stoma will begin to close
      • If < 7 days old, recannulate under direct visualization with fiberoptics
      • If > 7 days, use direct visualization
    • Obstruction
      • Mucous plugs, blood clots, tube displacement
      • Remove inner cannula > suction trach > deflate cuff > remove trach > bag ventilate or intubate
    • Hemorrhage
      • If > 48 hours since placement, consider TI fistula, infection, coagulopathy, aggressive suctioning
      • Should be evaluated by surgeon
  • Urgent complications = TE fistula, tracheal stenosis, infection, cutaneous fistula
  • Tracheo-innominate artery fistula
    • Sentinel bleed occurs in 50% of patients
    • Management
      • External compression over sternal notch
      • Internal compression with hyperinflated cuff (up to 50 cc of air)
      • Remove trach > oral or stomal intubation > hyperinflate cuff
      • ET tube beyond fistula > digital compression of artery against manubrium

PEM Lecture – HEENT Problems with Dr. Lund

  • Otitis media
    • Antibiotics duration by age
      • < 2 yrs – 10 days
      • 2-5 yrs – 7 days
      • > 6 yrs – 5 days
    • Antibiotics of choice
      • Amoxicillin high dose (90 mg/kg/day)
      • Augmentin – if amox in last 30 days or concurrent conjunctivitis
      • Ceftriaxone – IV or IM x3 days 50 mg/kg
      • Allergies – non-severe = cefdinir, cefpodoxime; severe = clindamycin
  • Neck Masses
    • Thyroglossal Duct Cyst
      • Most common neck mass
      • Moves with swallowing
      • Can get infected – treated with clindamycin, augmentin, Keflex
    • Brachial Cleft
      • Treat the same as thyroglossal duct cyst > refer to ENT
    • Fibromatosis Coli
      • Result of neonatal torticollis causing shortening of SCM muscle
    • Lymphadenitis
      • Could be caused by bacterial infection of 1+ node, mycobacterium, cat scratch disease
  • Post operative tonsillectomy bleeding
    • Management
      • Suction, IV placement
      • Lean forward
      • Direct pressure laterally with Magills or long clamp
      • Nebulized TXA
  • Epiglottitis
    • Keep calm, avoid aggressive exam maneuvers
    • Inhalational anesthesia with no paralytics
    • Needle cric as temporizing measure
    • Antibiotics – cefotaxime or ceftriaxone AND clindamycin or vancomycin

There is always a better option

We have many meds to choose from for emergency intubations. Sometimes we use propofol works well (status epilepticus, severe hypertension), sometimes versed/fentanyl (severe pain, head injured), methohexital (if you have a time machine and are intubating in 1999), thiopental (your toxicologist needs consults) and of course ketamine is basically always the best choice (if their BP is already too high just add propofol).

Etomidate is an ok drug, decent for intubation and sometimes helpful for sedation for imaging or even for a procedure (watch out for myoclonus). But I usually point out that there is always a better option than etomidate.

This meta-analysis of only 11 studies looked at etomidate vs other agents for intubations in critically ill patients. The summary seems to support the “always a better option than etomidate statement.” See results below, how about that number needed to harm?!

Results

We included 11 randomized trials comprising 2704 patients. We found that etomidate increased mortality (319/1359 [23%] vs. 267/1345 [20%]; risk ratio (RR) = 1.16; 95% confidence interval (CI), 1.01–1.33; P = 0.03; I2 = 0%; number needed to harm = 31). The probabilities of any increase and a 1% increase (NNH ≤100) in mortality were 98.1% and 92.1%, respectively.

Conclusions

This meta-analysis found a high probability that etomidate increases mortality when used as an induction agent in critically ill patients with a number needed to harm of 31.